Uterine natural killer cells and successful pregnancy: from mouse experiments to human physiology

Uterine natural killer (uNK) cells, a specific type of (NK) are important cells at the foeto-maternal interface in humans as well mice. uNK part innate lymphoid group 1. Especially mouse, but also rat, many vivo studies have been performed to evaluate role placental development. These shown that not indispensable pregnancy, they play an optimal decidual angiogenesis early trophoblast invasion and spiral artery remodelling mouse placenta. Based on studies, various vitro immunohistological human placenta from elective abortions, similar functions In present narrative review, development rat will be discussed first. Thereafter, reviewed these light knowledge cells.